In a study funded by the NIH, researchers from Drexel University in Pennsylvania, analyzed data from Medicaid and fee-for-service Medicare beneficiaries aged 30+ (2014–2016) found that autistic individuals had a 4x greater increase in dementia diagnoses compared to the general Medicare population.
Findings were consistent with their previous research. Future research should address factors that might contribute to the cooccurrence of neurodevelopmental and neurodegenerative conditions, as well as biological mechanisms of shared pathophysiology.
Vivanti, G., Lee, W. L., Ventimiglia, J., Tao, S., Lyall, K., & Shea, L. L. (2025). Prevalence of Dementia Among US Adults With Autism Spectrum Disorder. JAMA network open, 8(1), e2453691-e2453691.
Table 1. Characteristics of the 2 Groups of Interest Stratified According to Demographics and Features Known to Be Associated With Risk of Dementia
Table 2. Odds Ratios (ORs) of Dementia in the 3 Groups According to Age Group, Sex, Race, Urbanicity, and Presence or Absence of Diagnoses Including Depression, Other Psychiatric Conditions, and Cardiovascular Disease Risk Factors, Controlling for State of Enrollment
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